Journal: Diabetologia

Article Title: Association of CREBRF variants with obesity and diabetes in Pacific Islanders from Guam and Saipan

doi: 10.1007/s00125-019-4932-z

Figure Lengend Snippet: (a) ‘Bean’ plot of the distribution of BMI according to genotypes at rs12513649. Grey horizonal lines represent individual values, with the length of the line corresponding to the number of observations at each level. The symmetrical plots represent the density at each BMI level, estimated using the kernel density estimation function in SAS. Black horizontal bars represent the mean value. β=1.55 kg/m2 per copy of the G allele; p=0.0026. (b) ‘Bean’ plot of the distribution of BMI according to genotypes at rs373863828. β=1.48 kg/m2 per copy of the A allele; p=0.033. (c) Prevalence of diabetes according to genotype at rs12513649. OR 0.63 per copy of the G allele; p=0.0063. (d) Prevalence of diabetes according to genotype at rs373863828. OR 0.49 per copy of the A allele; p=0.0022. (e) Meta-analysis of the association of the A allele at rs373863828 with BMI, including data from the present study (labeled ‘Guam/Saipan’). Data are presented as the regression coefficient (β, kg/m2 per copy of the A allele) with 95% CI. (f) Meta-analysis of the association of the A allele at rs373863828 with diabetes. Data are presented as OR per copy of the A allele with 95% CI. NZ, New Zealand

Article Snippet: The symmetrical plots represent the density at each BMI level, estimated using the kernel density estimation function in SAS.

Techniques: Labeling

Journal: Computational and Structural Biotechnology Journal

Article Title: Single-molecule optical microscopy of protein dynamics and computational analysis of images to determine cell structure development in differentiating Bacillus subtilis

doi: 10.1016/j.csbj.2020.06.005

Figure Lengend Snippet: . Stoichiometry of SpoIIE in the mother cell. Kernel density estimation (KDE) of the stoichiometry (i.e. number of SpoIIE molecules per detected fluorescent focus) in mother cell with predicted overlap tetramer model (black dotted line).Chi-squared χ 2 and probability of confidence p values indicated. Stage I (green),II i (orange), II ii (red), II iii (yellow) and III (cyan). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)

Article Snippet: Kernel density estimation (KDE) of the stoichiometry (i.e. number of SpoIIE molecules per detected fluorescent focus) in mother cell with predicted overlap tetramer model (black dotted line).Chi-squared χ 2 and probability of confidence p values indicated.

Techniques:

Journal: Computational and Structural Biotechnology Journal

Article Title: Single-molecule optical microscopy of protein dynamics and computational analysis of images to determine cell structure development in differentiating Bacillus subtilis

doi: 10.1016/j.csbj.2020.06.005

Figure Lengend Snippet: . Stoichiometry of SpoIIE in the forespore. (A) Kernel density estimate (KDE) of forespore stoichiometry pooled for all data, and zoom-in (inset), (B) in separate stages with overlap tetramer model (black dotted line). (C) Bar chart of mean foci stoichiometry for foci which have > 20 molecules. Stage II ii statistically higher than II i (p = 0.007) (D) Mean number of foci detected per forespore. (E) Mean foci stoichiometry vs. normalised distance into spore for each stage, (inset) schematic of forespore distance normalization. Stage I (green),II i (orange), II ii (red), II iii (yellow) and III (cyan). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)

Article Snippet: Kernel density estimation (KDE) of the stoichiometry (i.e. number of SpoIIE molecules per detected fluorescent focus) in mother cell with predicted overlap tetramer model (black dotted line).Chi-squared χ 2 and probability of confidence p values indicated.

Techniques: